武汉大学公共卫生学院营养与食品卫生系
武汉市东湖路185号，430071
电话：18627149820
Email: lirui820@gmail.com

教育经历
2009－2013，营养学，博士，田纳西大学
2004－2008，生物学基地班，学士，武汉大学

所获奖项
Graduate Student Research Award, Experimental Biology, 波士顿, 麻省, 2013
Sadie K. Stanton Human Ecology Scholarship, 田纳西大学，2012-2013
ESPN Nutrition Award, 田纳西大学, 2012-2013
ESPN Nutrition Award, 田纳西大学, 2011-2012
Inez Lovelace and LoVera Lovelace McKenney Scholarship, 田纳西大学2011-2012
Helen Sharp Hakala Scholarship, 田纳西大学, 2010-2011
Sadie K. Stanton Human Ecology Scholarship, 田纳西大学，2009-2010
丙等讲学金, 武汉大学, 2007-2008
丙等讲学金, 武汉大学, 2006-2007
甲等奖学金, 武汉大学, 2004-2005

研究经历
博士: 田纳西大学营养系, 2009-2013 (导师: 陈国勋博士)
- 维生素A上调肝脏葡萄糖激酶(Gck)机制的研究
- 维生素A对肝脏Srebp-1c基因表达影响的机制研究.

本科 I: 武汉大学病毒学国家重点实验室, 2007-2008 (导师: 朱应博士)
- 白介素27在流感病毒感染过程中的机理研究

本科 II: 武汉大学保藏中心, 2006-2007 (导师: 郑从义博士)
- 乳腺癌基因Brca1可变剪切体的克隆构建

会员
美国营养协会
美国心脏协会

发表论文
1.Li, Y., Zhang, Y., Li, R., Chen, W., Howell, M., Zhang, R., and Chen, G. (2012). The Hepatic Raldh1 Expression Is elevated in Zucker Fatty Rats and Its Over-Expression Introduced the Retinal-Induced Srebp-1c Expression in INS-1 Cells. PLoS One 7, e45210.
2.Liu, L., Cao, Z., Chen, J., Li, R., Cao, Y., Zhu, C., Wu, K., Wu, J., Liu, F., and Zhu, Y. (2012). Influenza A Virus Induces Interleukin-27 through Cyclooxygenase-2 and Protein Kinase A Signaling. Journal of Biological Chemistry 287, 11899-11910.
3.Zhao, S., Li, R., Li, Y., Chen, W., Zhang, Y., and Chen, G. (2012). Roles of vitamin A status and retinoids in glucose and fatty acid metabolism. Biochem Cell Biol.
4.Zhang, Y., Chen, W., Li, R., Li, Y., Ge, Y., and Chen, G. (2011). Insulin-regulated Srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditions. PLoS One 6, e21342.
5.Ge, Y., Zhang, Y., Li, R., Chen, W., Li, Y., and Chen, G. (2011). Berberine regulated Gck, G6pc, Pck1 and Srebp-1c expression and activated AMP-activated protein kinase in primary rat hepatocytes. Int J Biol Sci 7, 673-684.
6.Zhang, Y., Li, R., Chen, W., Li, Y., and Chen, G. (2011). Retinoids induced Pck1 expression and attenuated insulin-mediated suppression of its expression via activation of retinoic acid receptor in primary rat hepatocytes. Mol Cell Biochem 355, 1-8.
7.Li, R., Chen, W., Li, Y., Zhang, Y., and Chen, G. (2011). Retinoids synergized with insulin to induce Srebp-1c expression and activated its promoter via the two liver X receptor binding sites that mediate insulin action. Biochem Biophys Res Commun 406, 268-272.
8.Liu, L., Li, R., Pan, Y., Chen, J., Li, Y., Wu, J., and Zhu, Y. (2011). High-throughput screen of protein expression levels induced by cyclooxygenase-2 during influenza a virus infection. Clin Chim Acta 412, 1081-1085.
9.Li, R., Zhang, R., Chen, W., Li, Y., Howell, M., and Chen, G. (2013). The role of RARα, RXRα, HNF4α, and COUP-TFII in the transcriptional regulation of hepatic glucokinase gene expression. (Submitted)
10.Zhang, R., Zhu, C., Bai, L., Li, R., Cao, Y., He, H., You, J., Liu, Y., Liu, F., Wu, K., and Wu, J. (2012). Hepatitis B virus induces expression of collagen triple helix repeat containing 1, a key regulator in the development of hepatocellular carcinoma. (Submitted)

国际会议报告
1.Li, R. and Chen, G. (2012/4/21). Identification of the retinoic acid response element in hepatic glucokinase gene promoter. Experimental Biology, 圣地亚哥, 加州，美国
2.Li, R. and Chen, G. (2012/3/2). Determination of the retinoic acid response element in the liver glucokinase gene promoter using deletion and linker-scan analysis. 奥本大学, 奥本, 阿拉巴马，美国
3.Li, R., Li, Y., and Chen, G. (2011/4/11) Regulatory Role of Retinoic Acid in Glucokinase and Sterol Regulatory Element-binding Protein-1c Expression. Experimental Biology, 华盛顿, 哥伦比亚特区，美国
4.Li, R., and Chen, G. (2010/4/25) Zucker Lean and Fatty Rat Hepatocytes Respond Differently to Insulin and Retinoids in the Expression of Glucose and Lipid Metabolic Genes. Experimental Biology, 安娜海姆, 加州，美国